• Categories:Medical knowledge
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• Time of issue:2020-06-30
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(Summary description)　　Source: China Food and Drug Administration website

　　When we inject penicillin drugs in the hospital, we often need to do a skin test. But do penicillin drugs through other routes of administration need to be tested? According to the "Yantai Evening News" report, a patient with toothache took 2 amoxicillin capsules by himself. After 10 minutes of taking the medicine, he suddenly experienced itching, palpitation, and difficulty breathing. After the allergic symptoms were released from the danger after first aid, it was discovered after questioning that the patient had a history of penicillin allergy, and amoxicillin was a penicillin antibacterial drug, which caused the allergic reaction.

　　Experts emphasized: According to the "Guiding Principles for the Clinical Application of Antimicrobial Drugs", penicillin drugs must be tested for penicillin skin sensitivity, whether they are intramuscularly, intravenously or orally administered. Once anaphylactic shock occurs, the drug should be discontinued immediately, and the patient should lie down immediately to facilitate the blood supply to the brain and keep warm. Residents generally do not have the ability to deal with anaphylactic shock, and should seek medical attention as soon as possible when allergic reactions occur. The doctor should immediately inject epinephrine into the patient and give oxygen inhalation, while applying anti-shock therapy such as blood pressure drugs and adrenocortical hormones.